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Sempionatto Lab, Rice University

Wearables Hardware Intern · May to Aug 2025

overview

The Sempionatto Lab makes wearable sensors that read your body chemistry straight from sweat. No blood draw, no lab. I worked on the whole stack over the summer: printing electrodes onto flexible Kapton film, checking them under a digital microscope, designing the analog circuitry in KiCad, and writing the firmware to pull readings off the sensors. The goal was a patch you could stick on your wrist and get continuous biomarker data from without having to do anything.

electrode fabrication

Carbon electrodes screen-printed onto flexible Kapton in separate passes for working, reference, and counter. Ion-selective membranes go on top after.

characterization

VHX digital microscope to check electrode geometry and surface quality before and after membrane application. You can see a lot go wrong at this step.

flexible assemblies

Multi-electrode arrays on flexible Kapton, thin enough to sit flat against skin.

circuit design

Analog front-end for ion-selective electrodes: INA333 instrumentation amps, DAC-driven reference bias, analog mux, ESP32 for wireless, and a boost plus LDO power path off a 3.7 V LiPo.